What is the most common side effect of isoniazid?
Common side effects may include: numbness, tingling, or burning pain in your hands or feet; nausea, vomiting, upset stomach; or. abnormal liver function tests.
What are common adverse reactions to TB treatment?
Common side effects
- feeling sick or dizzy.
- skin rashes.
- pins and needles.
- flu like symptoms.
- In very few cases people may experience jaundice, which is the yellowing of skin or eyes. If this happens, stop taking your medication and tell your doctor straight away.
What should I monitor with isoniazid?
Use should be carefully monitored in the following groups: daily users of alcohol, active chronic liver disease, severe renal dysfunction, age >35 years, concurrent use of any chronically administered drug, history of previous isoniazid discontinuation, existence of or conditions predisposing to peripheral neuropathy.
What is the most common adverse effect of first line drug therapy for TB?
The most common serious adverse event was rash and/or drug fever.
What is isoniazid side effects?
What are the possible side effects of isoniazid?
- sudden weakness or ill feeling, or fever for 3 days or longer;
- pain in your upper stomach (may spread to your back), nausea, loss of appetite;
- dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- vision changes, pain behind your eyes;
Which symptoms may occur when a patient takes carbamazepine with isoniazid?
What you should do about this interaction: If you experience drowsiness, dizziness, or blurred vision, contact your doctor. Your doctor may need to monitor your blood levels and adjust the dose of your medicine. Contact your doctor right away if you have any abdominal pain or yellowing of the eyes or skin.
What drugs interact with isoniazid?
Isoniazid interacts principally with anticonvulsants, theophylline, benzodiapines, paracetamol (acetaminophen) and some food. Fluoroquinolones can have absorption disturbance due to a variety of agents, especially the metal cations.
Can TB medication affect kidneys?
Hyderabad: Anti-tuberculosis drugs like rifampin, ethambutol and isoniazid are found to cause acute kidney damage in patients above 60, according to data studied by researchers.
How do I reduce the side effects of isoniazid?
Your doctor may also want you to take pyridoxine (e.g., Hexa-Betalin, vitamin B 6) every day to help prevent or lessen some of the side effects of isoniazid. This is not usually needed in children, who receive enough pyridoxine in their diet.