What is Serenoa repens used for?

Saw palmetto (also known as Serenoa repens) is commonly used to treat symptoms of benign prostatic hypertrophy (BPH) by inhibiting the 5α-reductase enzyme that converts testosterone to 5-dehydrotestosterone, prostaglandin synthesis, and growth factor actions.

Is Serenoa repens safe?

Currently available data suggest that S. repens is well tolerated by most users and is not associated with serious adverse events. The majority of adverse events are mild, infrequent and reversible, and include abdominal pain, diarrhoea, nausea and fatigue, headache, decreased libido and rhinitis.

How does Serenoa repens work?

Studies suggest that Serenoa repens is an inhibitor of both type 1 & 2 5a-reductases which are enzymes required for the conversion of testosterone to the more potent androgen 5a-dihydrotestosterone (DHT). This is similar to current prescription products for BPH, dutasteride (Avodart) and finasteride (Proscar).

Where does Serenoa repens come from?

SOURCE AND CONTENTS OF SERENOA REPENS Saw palmetto is an extract from the berries of the palm tree saw palmetto (also called serenoa repens, serenoa serrulata or sabal serrulata). The plant is a native of West Indies and is grown in plenty on the Atlantic southeast coast of North America.

Does saw palmetto increase testosterone in females?

Myth: Saw palmetto does nothing for females For example, it may have an estrogen-like effect and balance out the effects of testosterone. Saw palmetto may also help reduce high levels of androgens and prolactin in females with polycystic ovary syndrome (PCOS). Females with PCOS have elevated levels of male hormones.

Is finasteride really that bad?

Finasteride is generally safe to take for a long time. Many people take it for many months or even years without any problems. However, there have been reports of breast cancer in some men taking finasteride, but this is rare.