Is GeneReviews a journal?

Is GeneReviews a journal?

GeneReviews, an international point-of-care resource for busy clinicians, provides clinically relevant and medically actionable information for inherited conditions in a standardized journal-style format, covering diagnosis, management, and genetic counseling for patients and their families.

Is GeneReviews peer reviewed?

GeneReviews is an online database containing standardized peer-reviewed articles that describe specific heritable diseases. It was established in 1997 as GeneClinics by Roberta A Pagon (University of Washington) with funding from the National Institutes of Health.

How do you reference GeneReviews?

References. Pagon RA, Adam MP, Bird TD, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014.

Are there prenatal tests for hemochromatosis?

Prenatal testing: Although prenatal testing for a pregnancy at increased risk is possible once the HFE pathogenic variants have been identified in an affected family member, prenatal testing is not usually performed because HFE hemochromatosis is an adult-onset, treatable disorder with low clinical penetrance.

What happens when gene regulation goes wrong?

Upon gene expression, a segment of DNA is copied into another molecule called RNA. When gene regulation goes wrong, diseases like cancer can occur. Therefore, knowing how enzymes — highly efficient protein nanomachines — work to switch genes on and off enables the development of new drugs and diagnostics.

How are immediate early genes activated?

Immediate Early Genes Are Activated by Latent Transcription Factors After Learning. Immediate early gene (IEG) expression is directly induced by latent transcription factors, so protein synthesis is not required for expression of these genes after a stimulus.

How do you reference Blastp?

For the command-line version of NCBI BLAST, and for details of the BLAST method, you would cite:

1. Camacho C. et al.
2. Altschul S.F. et al. (1997) “Gapped BLAST and PSI-BLAST: a new generation of protein database search programs”
3. Altschul S.F. et al. (1990) “Basic local alignment search tool”