How much does mozobil cost?
The cost for Mozobil subcutaneous solution (20 mg/mL) is around $9,255 for a supply of 1.2 milliliters, depending on the pharmacy you visit….Subcutaneous Solution.
| Quantity | Per unit | Price |
|---|---|---|
| 1.2 milliliters | $7,712.18 | $9,254.61 |
What type of drug is Mozobil?
Mozobil (plerixafor injection) is a hematopoietic stem cell mobilizer that helps bone marrow release stem cells into the bloodstream so they can be collected and transplanted back into the body, used in people with non-Hodgkin’s lymphoma or multiple myeloma.
What is Mozobil used for?
Mozobil is a mobilization agent for those who have been diagnosed with non-Hodgkin’s lymphoma (NHL) or multiple myeloma (MM) and are expected to eventually undergo an autologous hematopoietic cell transplantation (autologous HCT).
When should I take Mozobil?
Administer Mozobil approximately 11 hours prior to initiation of each apheresis for up to 4 consecutive days. The recommended dose of Mozobil by subcutaneous injection is based on body weight: • 20 mg fixed dose or 0.24 mg/kg of body weight for patients weighing ≤83 kg.
How is Mozobil administered?
Mozobil is a subcutaneous injection indicated in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin’s lymphoma (NHL) or multiple myeloma (MM).
What is stem cell mobilization?
Listen to pronunciation. (stem sel MOH-bih-lih-ZAY-shun) A process in which certain drugs are used to cause the movement of stem cells from the bone marrow into the blood. The stem cells can be collected and stored.
How do you administer Mozobil?
It should be administered by subcutaneous injection 6 to 11 hours prior to initiation of each apheresis following 4 day pre-treatment with G-CSF. In clinical trials, Mozobil has been commonly used for 2 to 4 (and up to 7) consecutive days.
What is Mozobil injection?
How is Mozobil given?
Mozobil is given as an injection in a hospital or clinic setting. Before receiving Mozobil, you will be given another medication that will help your bone marrow produce stem cells and certain white blood cells that help support your immune system.
Who makes Mozobil?
Plerixafor (INN and USAN, trade name Mozobil) is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients into the bloodstream. The stem cells are then extracted from the blood and transplanted back to the patient. The drug was developed by AnorMED, which was subsequently bought by Genzyme.
How long does stem cell mobilization take?
This process may take approximately 4–6 hours to complete each day. Repeated collections on subsequent days may be needed to collect enough stem cells for your transplant.
What kind of injection is Mozobil?
Mozobil (plerixafor) injection is a sterile, preservative-free, clear, colorless to pale-yellow, isotonic solution for subcutaneous injection. Each mL of the sterile solution contains 20 mg of plerixafor.
What is the recommended storage temperature for Mozobil?
Store at 25°C (77°F); excursions permitted to 15°C-30°C (59°F-86°F). [see USP Controlled Room Temperature] Each vial of Mozobil is intended for single use only. Any unused drug remaining after injection must be discarded. Distributed by: Genzyme Corporation 500 Kendall Street Cambridge, MA 02142 USA A SANOFI COMPANY.
What is Mozobil (plerixafor)?
Mozobil (plerixafor) injection is a sterile, preservative-free, clear, colorless to pale-yellow, isotonic solution for subcutaneous injection.
What are the possible side effects of Mozobil in patients with NHL?
In the randomized studies, 34% of patients with NHL or MM had mild to moderate injection site reactions at the site of subcutaneous administration of Mozobil. These included erythema, hematoma, hemorrhage, induration, inflammation, irritation, pain, paresthesia, pruritus, rash, swelling, and urticaria.
