Does bendamustine cause weight loss?
Goals of therapy: Bendamustine + rituximab is given to shrink lymph nodes and decrease symptoms from b-cell lymphoma such as fevers, night sweats, and weight loss.
Does bendamustine cause weight gain?
Call your doctor right away if you have a decrease or change in urine amount, joint pain, stiffness, or swelling, lower back, side, or stomach pain, a rapid weight gain, swelling of the feet or lower legs, or unusual tiredness or weakness.
What are the long term effects of bendamustine?
10.8% of these cases were new types of cancer, including non-melanoma skin cancer (57.1%), prostate cancer (14.3%), and renal cancer (14.3%). 62.9% of patients also reported infections. The most common infections were pneumonia (28.4%), upper respiratory infection (27.3%), and herpes (15.5%).
Does bendamustine make you tired?
One small study compared treatment with bendamustine to treatment with chlorambucil (a different chemotherapy drug) in people with untreated CLL. In this study, 9% of people taking bendamustine had fatigue. In comparison, 6% of people taking chlorambucil had fatigue.
Does Rituxan cause weight loss?
Weight loss The drug itself shouldn’t cause you to lose weight. However, nausea and diarrhea (side effects of Rituxan) may cause weight loss. Infection is another side effect of the medication that may cause you to lose weight.
How effective is bendamustine and rituximab?
Based on the willingness-to-pay threshold of $50,000 per QALY, bendamustine plus rituximab was the more cost-effective strategy than R-CHOP 66% of the time in follicular lymphoma, 82% in mantle-cell lymphoma, 64% in marginal zone lymphoma, and 86% in lymphoplasmacytic lymphoma.
Does bendamustine cause heart problems?
Heart problems like heart failure have happened in people taking this drug. Sometimes, this has been deadly. Call your doctor right away if you have chest pain or pressure, a heartbeat that does not feel normal, shortness of breath, a big weight gain, or swelling in the arms or legs.
Is bendamustine a chemo drug?
Bendamustine is a type of chemotherapy drug called an alkylating agent.
Is bendamustine an irritant?
Bendamustine is identified as an irritant with vesicantlike properties in various drug resources. It is classified as an irritant in some literature and as a vesicant in the ESMO-EONS 2012 guideline.
Does Rituxan cause loss of appetite?
Check with your doctor right away if you have bloody urine, a decrease in frequency or amount of urine, an increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, troubled breathing, unusual tiredness or weakness, vomiting, or weight …
Can Rituxan cause weight gain?
Weight gain or weight loss Some people took Rituxan afterward and some people didn’t take any medication. Of the people who took Rituxan after chemotherapy, 11% gained weight. In comparison, 4% of people who didn’t take medication after chemotherapy gained weight.
How safe is bendamustine?
Overall, bendamustine was well tolerated. The most common hematologic adverse events reported were anemia (89%), thrombocytopenia (77%), and neutropenia (75%). Laboratory values should be monitored on a weekly basis. Hematologic nadir typically occurs during week 3 of treatment.