Can selegiline be used in cats?

Selegiline (brand names: Anipryl®, Eldepryl®, l-deprenyl, Selgian®, Zelapar®) is a monoamine oxidase inhibitor (MAOI) used to treat signs due to cognitive dysfunction syndrome in dogs and cats. It has also been used to treat pituitary dependent Cushing’s disease, although its effectiveness has not been proven.

How long does it take for selegiline to take effect?

Selegiline is the only FDA-approved treatment for canine cognitive dysfunction. Although the onset of action can be variable (between four and12 weeks), most dogs show some improvement after one month of treatment and there may be continued improvement over time.

What are the side effects of selegiline?

Selegiline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

dizziness.
lightheadedness.
fainting.
dry mouth.
nausea.
vomiting.
stomach pain.
difficulty swallowing.

What is selegiline medication used for?

Selegiline is used in combination with levodopa or levodopa and carbidopa combination to treat Parkinson’s disease (sometimes called “shaking palsy” or “paralysis agitans”). This medicine works to increase and extend the effects of levodopa, and may help to slow the progress of Parkinson’s disease.

What foods should you avoid when taking selegiline?

While taking selegiline and for 14 days after you stop, you must NOT eat foods that are high in tyramine, including:

air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring;
any spoiled or improperly stored beef, poultry, fish, or liver;

Can selegiline be taken alone?

Selegiline has been well tolerated when given alone. The most frequent adverse events seen during monotherapy have been insomnia, nausea, benign cardiac arrhythmias, dizziness and headache.

Can selegiline cause serotonin syndrome?

Selegiline may cause a condition called serotonin syndrome when used together with certain MAO inhibitors (eg, phenelzine, rasagiline, tranylcypromine) and medicines to treat depression (eg, amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac …

Does selegiline affect sleep?

Insomnia and sleep disorder were reported as very common side effects with selegiline in double-blind placebo-controlled clinical trials at a higher frequency when used as adjunctive therapy with levodopa in the earlier phases of Parkinson’s disease.

What foods should be avoided when taking selegiline?

What is selegiline HCl for dogs and cats used for?

Overview of Selegiline HCl for Dogs and Cats. Selegiline is a complex drug that affects brain function. The drug is also known as L-deprenyl, Eldepryl® and Anipryl®. Used primarily to treat feline and canine cognitive dysfunction syndrome (senility in older dogs and cats) and for Cushing’s disease in dogs.

Can you give selegiline to older dogs?

Selegiline is rarely used in cats. Specific criteria for the diagnosis of canine cognitive dysfunction syndrome should be fulfilled before treating with selegiline. Other causes of “senility” or abnormal behavior in older dogs should be excluded first, such as disorders of body chemistry, brain tumors and adverse reactions to other medications.

What is Anipryl (selegiline) for dogs used for?

What is Anipryl (Selegiline): Anipryl, also known as L-deprenyl, is a monoamine oxidase inhibitor (MAOi) used in dogs for the treatment of Cushing’s disease and canine cognitive dysfunction.